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Home Lifestyle Health

The Role of Sperm Morphology and DNA Fragmentation in ICSI Success

by swetha 234
July 21, 2025
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When patients begin ICSI treatment, there is always hope and a bit of confusion as well. One thing most people wonder about is – what actually influences the success of ICSI fertility treatment? The health of your sperm is just as important as the age and quality of your eggs. Particularly two things – sperm morphology and DNA fragmentation.

Let’s deconstruct what these are and how they affect your chances with ICSI.

What is Sperm Morphology?

Simply said, sperm morphology describes the size, shape, and arrangement of the sperm. A good sperm has a smooth oval head and a firm tail that enables it to swim normally. If the majority of sperm are irregularly shaped, it may not be able to fertilize the egg effectively even with ICSI.

Most couples go to a fertility clinic and think that if the sperm count is normal, then all is well. But in reality, bad morphology can still decrease the likelihood of success.

What is DNA Fragmentation in Sperm?

DNA, or genetic information, is present in every sperm and is utilized to generate a child.  When that DNA is broken or damaged, it fragments. High fragmentation is when even if sperm successfully fertilizes the egg, the embryo won’t develop normally.

This is one of the silent reasons why some couples have repeated IVF or ICSI failure despite everything appearing normal.

How These Two Factors Affect ICSI Treatment

In ICSI treatment for fertility, a single sperm is injected directly into the egg. Due to that, choosing a good quality sperm becomes more critical than ever.

Deteriorated morphology can result in failure of fertilization or embryonic development.

Low embryo quality, implantation failure, or miscarriage can all be caused by excessive DNA fragmentation.

That is why renowned clinics like Dr. Aravind’s IVF Fertility & Pregnancy Centre always test sperm health in depth prior to initiating ICSI.

Tests That Can Help

Contemporary fertility clinics now perform sophisticated tests to better know sperm quality:

Semen analysis for morphology, motility, and count.

DNA fragmentation test (DFI) to visualize the extent of sperm DNA damage.

Depending on these findings, physicians can recommend lifestyle modifications, antioxidant pills, or even treatments such as PICSI or MACS to select healthier sperm for ICSI.

Where to Seek the Right Counselling?

If you are searching for the top fertility clinic near me, ensure that the center is equipped to deal with male factor infertility as well. A good clinic will always take time to interpret test results, provide tips on how to improve sperm quality, and recommend the best ICSI plan.

At Dr. Aravind’s IVF Fertility & Pregnancy Centre, several couples have succeeded even after failed cycles, simply because they received the right sperm assessment and treatment. The staff does not hurry the treatment – they tailor everything to your situation.

What Can You Do If Your Sperm Has Problems?

First, don’t worry. Most men who have low morphology or high DNA fragmentation have become dads with the proper assistance.

Following are a few steps that could enhance sperm quality:

Stop smoking and cut down on alcohol

Consume antioxidant foods (fruits, nuts, vegetables)

Lessen stress

Maintain a healthy weight

Take supplements as prescribed by the doctor

Above all else, don’t delay.  Your prognosis with ICSI treatment improves with early initiation.

When it comes to ICSI fertility treatment, sperm quality matters as much as eggs. Understanding sperm morphology and DNA fragmentation is not just for doctors – even couples need to know how it can impact the result.

If you’re on the ICSI journey, take that extra step. Ask your fertility center to check sperm quality properly. Because the entire result can be altered by a single detail.

To receive expert guidance and the best treatment, go to Dr. Aravind’s IVF Fertility & Pregnancy Centre – where science and compassion blend together, and each couple is given a second chance to hope.

Tags: best fertility centrefertility centerivf centreivf cost
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